Rab3c Antikörper
Kurzübersicht für Rab3c Antikörper (ABIN2856623)
Target
Alle Rab3c Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
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Rabbit Polyclonal antibody to RAB3C (RAB3C, member RAS oncogene family)
RAB3C antibody [N1C3] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Full length human RAB3C Recombinant protein.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: Mouse brain , H1299 , rat brain
Validation: KO/KD, Orthogonal, Overexpression
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.94 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis." in: Molecular cancer, Vol. 16, Issue 1, pp. 135, (2018) (PubMed).
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: "Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis." in: Molecular cancer, Vol. 16, Issue 1, pp. 135, (2018) (PubMed).
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- Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))
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Andere Bezeichnung
- RAB3C, member RAS oncogene family
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Hintergrund
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RAB proteins, such as RAB3C, are small GTPases implicated in the regulation of vesicular trafficking between membrane compartments (Cheng et al., 2002 [PubMed 12296628]).[supplied by OMIM]
Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side -
Molekulargewicht
- 26 kDa
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Gen-ID
- 115827
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UniProt
- Q96E17
Target
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