ZWINT Antikörper (Center)

Produktnummer ABIN2856493

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ZWINT in WB, IF und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für ZWINT Antikörper (Center) (ABIN2856493)

Target: ZWINT (ZW10 Interactor (ZWINT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZWINT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-ZWINT Antikörper

Bindungsspezifität: Center

Produktmerkmale: Rabbit Polyclonal antibody to ZWINT (ZW10 interactor)
ZWINT antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ZWINT. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-ZWINT Antikörper (ABIN2856493)

Zhou, Wang, Zheng, Teng, Chen: "Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2." in: Nature communications, Vol. 7, pp. 10151, (2016) (PubMed).

Details zu ZWINT

Target: ZWINT (ZW10 Interactor (ZWINT))

Andere Bezeichnung: ZWINT

Hintergrund: This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Nucleus , Kinetochore

Molekulargewicht: 31 kDa

Gen-ID: 11130