WHSC1 Antikörper (N-Term)

Produktnummer ABIN2856315

Dieses Anti-WHSC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von WHSC1 in WB und IHC (p). Geeignet für Human.

Kurzübersicht für WHSC1 Antikörper (N-Term) (ABIN2856315)

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WHSC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-WHSC1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Mouse (83 %)

Produktmerkmale: Rabbit Polyclonal antibody to NSD2 (Wolf-Hirschhorn syndrome candidate 1)
NSD2 antibody [N1], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human NSD2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Andere Bezeichnung: NSD2

Hintergrund: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Molekulargewicht: 152 kDa

Gen-ID: 7468

Pathways: SARS-CoV-2 Protein Interaktom