CD2-Associated Protein (Cd2ap) (Center) Antikörper

Details zu Produkt Nr. ABIN2856284
Antigen
Epitop
Center
5
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
48
30
26
Wirt
Kaninchen
50
2
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
43
26
19
7
7
3
3
1
1
1
Optionen
Immunogen Recombinant protein encompassing a sequence within the center region of human CD2AP. The exact sequence is proprietary.
Isotyp IgG
Produktmerkmale Rabbit Polyclonal antibody to CD2AP (CD2-associated protein)
CD2AP antibody
Reinigung Purified by antigen-affinity chromatography.
Antigen
Andere Bezeichnung CD2AP (Cd2ap Antibody Abstract)
Hintergrund This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , ruffle
Molekulargewicht 71 kDa
Gen-ID 23607
Applikations-hinweise Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
Kommentare

Positive Control: 293T , A431 , HeLa , HepG2 , A375 , Rat2

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Konservierungs-mittel Thimerosal (Merthiolate)
Vorsichtsmaßnahmen This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-CD2-Associated Protein (Cd2ap) (Center) antibody (ABIN2856284) WB Image CD2AP antibody detects CD2AP protein by Western blot analysis. A. 30 µg Rat2...
Image no. 2 for anti-CD2-Associated Protein (Cd2ap) (Center) antibody (ABIN2856284) ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde...
Image no. 3 for anti-CD2-Associated Protein (Cd2ap) (Center) antibody (ABIN2856284) IHC-P Image Immunohistochemical analysis of paraffin-embedded FaDu xenograft, using C...
Image no. 4 for anti-CD2-Associated Protein (Cd2ap) (Center) antibody (ABIN2856284) IHC-P Image CD2AP antibody detects CD2AP protein at cytosol on mouse colon by immunoh...
Image no. 5 for anti-CD2-Associated Protein (Cd2ap) (Center) antibody (ABIN2856284) WB Image CD2AP antibody detects CD2AP protein by Western blot analysis. A. 30 µg 293T...