CASQ2 Antikörper

Produktnummer ABIN2856218

Der Kaninchen Polyklonal Anti-CASQ2-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, CASQ2 in Proben von Human zu detektieren.

Kurzübersicht für CASQ2 Antikörper (ABIN2856218)

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASQ2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CASQ2 Antikörper

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit polyclonal antibody to Calsequestrin-2 (calsequestrin 2 (cardiac muscle))
Calsequestrin-2 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Calsequestrin 2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HCT116

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.68 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CASQ2

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Andere Bezeichnung: calsequestrin 2

Hintergrund: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Cellular Localization: Sarcoplasmic reticulum lumen

Molekulargewicht: 46 kDa

Gen-ID: 845

UniProt: O14958

Pathways: Negative Regulation of Transporter Activity