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NK2 Homeobox 5 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NK2 Homeobox 5 in WB, IF, ICC und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2856166

Kurzübersicht für NK2 Homeobox 5 Antikörper (ABIN2856166)

Target

Alle NK2 Homeobox 5 (NKX2-5) Antikörper anzeigen
NK2 Homeobox 5 (NKX2-5)

Reaktivität

  • 41
  • 20
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 42
  • 8
  • 1
Kaninchen

Klonalität

  • 44
  • 7
Polyklonal

Konjugat

  • 41
  • 3
  • 2
  • 2
  • 2
  • 1
Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert

Applikation

  • 43
  • 29
  • 8
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Rabbit Polyclonal antibody to Nkx2.5 (NK2 transcription factor related, locus 5 (Drosophila))
    Nkx2.5 antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human Nkx2.5. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Validation: Comparison

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.21 mg/mL

    Buffer

    1XPBS, 20 % Glycerol ( pH 7), 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    NK2 Homeobox 5 (NKX2-5)

    Andere Bezeichnung

    NK2 homeobox 5

    Hintergrund

    Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]

    Cellular Localization: Nucleus

    Molekulargewicht

    35 kDa

    Gen-ID

    1482

    UniProt

    P52952

    Pathways

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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