FKBP3 Antikörper (Center)
Kurzübersicht für FKBP3 Antikörper (Center) (ABIN2856136)
Target
Alle FKBP3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Kreuzreaktivität
- Ratte (Rattus), Rind (Kuh), Xenopus tropicalis
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Kreuzreaktivität (Details)
- Rat (94 %), Bovine (97 %), Xenopus tropicalis (81 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to FKBP25 (FK506 binding protein 3, 25 kDa)
FKBP25 antibody [N1C3] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human FKBP25. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Kommentare
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Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.53 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
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Andere Bezeichnung
- FKBP25
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Hintergrund
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Cellular Localization: Nucleus -
Molekulargewicht
- 25 kDa
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Gen-ID
- 2287
Target
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