NR0B1 Antikörper

Produktnummer ABIN2856058

Produktdetails anti-NR0B1 Antikörper

Target: NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR0B1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to NR0B1 (nuclear receptor subfamily 0, group B, member 1)
NR0B1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NR0B1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NR0B1

Target: NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))

Andere Bezeichnung: nuclear receptor subfamily 0 group B member 1 (NR0B1 Produkte)

Synonyme: DAX antikoerper, NR0B1 antikoerper, dax1 antikoerper, AHC antikoerper, AHCH antikoerper, AHX antikoerper, DAX-1 antikoerper, DAX1 antikoerper, DSS antikoerper, GTD antikoerper, HHG antikoerper, NROB1 antikoerper, SRXY2 antikoerper, Ahc antikoerper, Ahch antikoerper, Dax1 antikoerper, nuclear receptor subfamily 0 group B member 1 antikoerper, nuclear receptor subfamily 0, group B, member 1 antikoerper, nuclear receptor subfamily 0 group B member 1 L homeolog antikoerper, NR0B1 antikoerper, nr0b1 antikoerper, nr0b1.L antikoerper, Nr0b1 antikoerper

Hintergrund: This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

Cellular Localization: Nucleus , Cytoplasm

Molekulargewicht: 52 kDa

Gen-ID: 190

UniProt: P51843

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling