PSMA6 Antikörper (Center)
Kurzübersicht für PSMA6 Antikörper (Center) (ABIN2856025)
Target
Alle PSMA6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Kreuzreaktivität
- Ratte (Rattus), Schaf, Rhesusaffen, Schimpanse, Rind (Kuh)
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Kreuzreaktivität (Details)
- Rat (100 %), Sheep (100 %), Rhesus Monkey (100 %), Chimpanzee (100 %), Bovine (100 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to Proteasome 20S alpha 6 (proteasome (prosome, macropain) subunit, alpha type, 6)
Proteasome 20S alpha 6 antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human Proteasome 20S alpha 6. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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Kommentare
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Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Raji , mouse brain
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PSMA6 (Proteasome Subunit alpha 6 (PSMA6))
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Andere Bezeichnung
- Proteasome 20S alpha 6
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Hintergrund
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.
Cellular Localization: Cytoplasm , Nucleus -
Molekulargewicht
- 27 kDa
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Gen-ID
- 5687
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Target
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