GPC1 Antikörper
Kurzübersicht für GPC1 Antikörper (ABIN2855849)
Target
Alle GPC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
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Rabbit Polyclonal antibody to Glypican 1 (glypican 1)
Glypican 1 antibody [N3C3] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human Glypican 1. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: MDA-MB-231 , MDA-MB-231 (24 μg/ml Tunicamycin for 16hr) , U87-MG membrane extracts , U87-MG conditioned medium , Mouse brain , mouse fetal brain , A431 , MCF-7 , AsPC-1
Validation: Comparison, KO/KD, Orthogonal
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.58 mg/mL
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Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma." in: Cancer medicine, Vol. 6, Issue 6, pp. 1181-1191, (2018) (PubMed).
: "α3 Chains of type V collagen regulate breast tumour growth via glypican-1." in: Nature communications, Vol. 8, pp. 14351, (2018) (PubMed).
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Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma." in: Cancer medicine, Vol. 6, Issue 6, pp. 1181-1191, (2018) (PubMed).
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- GPC1 (Glypican 1 (GPC1))
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Andere Bezeichnung
- glypican 1
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Hintergrund
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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
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Molekulargewicht
- 62 kDa
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Gen-ID
- 2817
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UniProt
- P35052
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Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
Target
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