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GPC1 Antikörper

Der Kaninchen Polyklonal Anti-GPC1-Antikörper wurde für WB, ELISA, ICC, IP, IF, IHC (p) und FACS validiert. Er ist geeignet, GPC1 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.
Produktnummer ABIN2855849

Kurzübersicht für GPC1 Antikörper (ABIN2855849)

Target

Alle GPC1 Antikörper anzeigen
GPC1 (Glypican 1 (GPC1))

Reaktivität

  • 58
  • 18
  • 16
Human

Wirt

  • 71
  • 10
  • 2
  • 1
Kaninchen

Klonalität

  • 71
  • 11
  • 1
Polyklonal

Konjugat

  • 31
  • 13
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GPC1 Antikörper ist unkonjugiert

Applikation

  • 38
  • 26
  • 26
  • 24
  • 22
  • 16
  • 8
  • 8
  • 7
  • 6
  • 6
  • 4
  • 2
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Güteklasse

KO Validated
  • Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Rabbit Polyclonal antibody to Glypican 1 (glypican 1)
    Glypican 1 antibody [N3C3]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human Glypican 1. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: MDA-MB-231 , MDA-MB-231 (24 μg/ml Tunicamycin for 16hr) , U87-MG membrane extracts , U87-MG conditioned medium , Mouse brain , mouse fetal brain , A431 , MCF-7 , AsPC-1

    Validation: Comparison, KO/KD, Orthogonal

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.58 mg/mL

    Buffer

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lu, Niu, Liu, Gao, Sun, Zhao: "Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma." in: Cancer medicine, Vol. 6, Issue 6, pp. 1181-1191, (2018) (PubMed).

    Huang, Ge, Izzi, Greenspan: "α3 Chains of type V collagen regulate breast tumour growth via glypican-1." in: Nature communications, Vol. 8, pp. 14351, (2018) (PubMed).

  • Target

    GPC1 (Glypican 1 (GPC1))

    Andere Bezeichnung

    glypican 1

    Hintergrund

    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

    Molekulargewicht

    62 kDa

    Gen-ID

    2817

    UniProt

    P35052

    Pathways

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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