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FPGT Antikörper

This anti-FPGT antibody (ABIN2855758) is a Rabbit Polyclonal antibody detecting FPGT in WB, IHC (p). Suitable for Human.
Produktnummer ABIN2855758

Kurzübersicht für FPGT Antikörper (ABIN2855758)

Target

Alle FPGT Antikörper anzeigen
FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Reaktivität

  • 36
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 36
  • 3
Kaninchen

Klonalität

  • 39
Polyklonal

Konjugat

  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FPGT Antikörper ist unkonjugiert

Applikation

  • 35
  • 13
  • 13
  • 10
  • 9
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit polyclonal antibody to FPGT (fucose-1-phosphate guanylyltransferase)
    FPGT antibody [N2C2], Internal

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human FPGT. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: Raji

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.74 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

    Andere Bezeichnung

    fucose-1-phosphate guanylyltransferase

    Hintergrund

    L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.

    Cellular Localization: Cytoplasm

    Molekulargewicht

    67 kDa

    Gen-ID

    8790

    UniProt

    O14772
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