FPGT Antikörper
Kurzübersicht für FPGT Antikörper (ABIN2855758)
Target
Alle FPGT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Kreuzreaktivität
- Human
- 
                                            Produktmerkmale
- 
                        Rabbit polyclonal antibody to FPGT (fucose-1-phosphate guanylyltransferase)
 FPGT antibody [N2C2], Internal
- 
                                            Aufreinigung
- Purified by antigen-affinity chromatography.
- 
                                            Immunogen
- Recombinant protein encompassing a sequence within the center region of human FPGT. The exact sequence is proprietary.
- 
                                            Isotyp
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 
                                            Kommentare
- 
                        Positive Control: Raji 
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 0.74 mg/mL
- 
                                            Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 
                                            Konservierungsmittel
- Thimerosal (Merthiolate)
- 
                                            Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C,-20 °C
- 
                                            Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
- 
                                            
- 
    - FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
- 
                                            Andere Bezeichnung
- fucose-1-phosphate guanylyltransferase
- 
                                            Hintergrund
- 
                        L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. 
 Cellular Localization: Cytoplasm
- 
                                            Molekulargewicht
- 67 kDa
- 
                                            Gen-ID
- 8790
- 
                                            UniProt
- O14772
 Target
- 
                    
 
                                     
                                     
                                    