GABRA1 Antikörper (Center)

Produktnummer ABIN2855751

Produktdetails anti-GABRA1 Antikörper

Target: GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Rhesusaffen, Rind (Kuh)

Kreuzreaktivität (Details): Rhesus Monkey (100 %), Bovine (100 %)

Produktmerkmale: Rabbit polyclonal antibody to GABA A Receptor alpha 1 (gamma-aminobutyric acid (GABA) A receptor, alpha 1)
GABA A Receptor alpha 1 antibody [N1C1]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: U87-MG , SK-N-SH

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.75 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu GABRA1

Target: GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

Andere Bezeichnung: GABA A Receptor alpha 1 (GABRA1 Produkte)

Synonyme: ECA4 antikoerper, EJM antikoerper, EJM5 antikoerper, zgc:153566 antikoerper, Gabra-1 antikoerper, gamma-aminobutyric acid type A receptor alpha1 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, alpha 1 antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 antikoerper, gamma-aminobutyric acid receptor subunit alpha-1 antikoerper, GABRA1 antikoerper, Gabra1 antikoerper, gabra1 antikoerper, LOC100653509 antikoerper

Hintergrund: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

Cellular Localization: Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein , Cell membrane, Multi-pass membrane protein

Molekulargewicht: 52 kDa

Gen-ID: 2554