GABRA1 Antikörper (Center)
Kurzübersicht für GABRA1 Antikörper (Center) (ABIN2855751)
Target
Alle GABRA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Kreuzreaktivität
- Rhesusaffen, Rind (Kuh)
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Kreuzreaktivität (Details)
- Rhesus Monkey (100 %), Bovine (100 %)
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Produktmerkmale
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Rabbit polyclonal antibody to GABA A Receptor alpha 1 (gamma-aminobutyric acid (GABA) A receptor, alpha 1)
GABA A Receptor alpha 1 antibody [N1C1] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 1. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Kommentare
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Positive Control: U87-MG , SK-N-SH
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.75 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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Andere Bezeichnung
- GABA A Receptor alpha 1
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Hintergrund
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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Cellular Localization: Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein , Cell membrane, Multi-pass membrane protein -
Molekulargewicht
- 52 kDa
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Gen-ID
- 2554
Target
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