IP6K1 Antikörper

Produktnummer ABIN2855731

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IP6K1 in WB, IP, ICC, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für IP6K1 Antikörper (ABIN2855731)

Target: IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IP6K1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Güteklasse: KO Validated

Produktdetails anti-IP6K1 Antikörper

Spezifität: Knockdown/Knockout validation was supported by references (PMID:27701146)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to IP6K1 (inositol hexakisphosphate kinase 1)
IP6K1 antibody

Aufreinigung: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IP6K1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Jurkat , Raji , NCI-H929

Validation: KO/KD, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.22 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-IP6K1 Antikörper (ABIN2855731)

Zhu, Ghoshal, Tyagi, Chakraborty: "Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain." in: Molecular metabolism, Vol. 6, Issue 1, pp. 73-85, (2018) (PubMed).

Details zu IP6K1

Target: IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))

Andere Bezeichnung: inositol hexakisphosphate kinase 1

Hintergrund: This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene, however, the full-length nature of all transcript variants has not yet been described.

Cellular Localization: Cytoplasm , Nucleus

Molekulargewicht: 50 kDa

Gen-ID: 9807

UniProt: Q92551