UAP1 Antikörper

Produktnummer ABIN2855661

Dieses Anti-UAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UAP1 in WB, IF, ICC und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für UAP1 Antikörper (ABIN2855661)

Target: UAP1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1 (UAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-UAP1 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to UAP1 (UDP-N-acteylglucosamine pyrophosphorylase 1)
UAP1 antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human UAP1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: H1299

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-UAP1 Antikörper (ABIN2855661)

Andres, Blong, Evans, Rumachik, Yamaguchi, Pham, Thompson, Kohler, Bertozzi: "Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation." in: ACS chemical biology, Vol. 12, Issue 8, pp. 2030-2039, (2018) (PubMed).

Details zu UAP1

Target: UAP1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1 (UAP1))

Andere Bezeichnung: UDP-N-acetylglucosamine pyrophosphorylase 1

Hintergrund: Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

Cellular Localization: Cytoplasm

Molekulargewicht: 59 kDa

Gen-ID: 6675

UniProt: Q16222