CYP2A6 Antikörper (Internal Region)

Produktnummer ABIN2855614

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CYP2A6 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CYP2A6 Antikörper (Internal Region) (ABIN2855614)

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2A6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CYP2A6 Antikörper

Bindungsspezifität: Internal Region

Produktmerkmale: Rabbit polyclonal antibody to Cytochrome P450 2A6 (cytochrome P450, family 2, subfamily A, polypeptide 6)
CYP2A antibody [C1C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CYP2A. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CYP2A6

Target: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Andere Bezeichnung: Cytochrome P450 2A6

Hintergrund: This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3, however, it has been renamed CYP2A6.

Cellular Localization: Endoplasmic reticulum membrane , Microsome membrane

Molekulargewicht: 57 kDa

Gen-ID: 1548