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ACTN1 Antikörper

Dieses Anti-ACTN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ACTN1 in WB, IHC (p) und IHC (wm). Geeignet für Human.
Produktnummer ABIN2855589

Kurzübersicht für ACTN1 Antikörper (ABIN2855589)

Target

Alle ACTN1 Antikörper anzeigen
ACTN1 (Actinin, alpha 1 (ACTN1))

Reaktivität

  • 58
  • 21
  • 18
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 46
  • 11
  • 1
Kaninchen

Klonalität

  • 48
  • 10
Polyklonal

Konjugat

  • 37
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ACTN1 Antikörper ist unkonjugiert

Applikation

  • 39
  • 25
  • 19
  • 15
  • 8
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))
  • Kreuzreaktivität

    Human, Maus, Ratte, Zebrafisch (Danio rerio)

    Produktmerkmale

    Rabbit Polyclonal antibody to alpha Actinin 1 (actinin, alpha 1)
    alpha Actinin 1 antibody [N2N3]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human alpha Actinin 1. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: NIH-3T3 , 293T , A431 , HeLa , HepG2 , PC-12 , Rat2 , rat brain

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.09 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    ACTN1 (Actinin, alpha 1 (ACTN1))

    Andere Bezeichnung

    actinin alpha 1

    Hintergrund

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk

    Molekulargewicht

    103 kDa

    Gen-ID

    87

    UniProt

    P12814

    Pathways

    Cell-Cell Junction Organization
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