LDH Antikörper

Produktnummer ABIN285556

Produktdetails

Target: LDH

Reaktivität: Kaninchen

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunoprecipitation (IP), ELISA, Western Blotting (WB)

Aufreinigung: LDH antibody was purified by delipidation and defibrination.

Immunogen: LDH antibody was raised in goat using full length lactate dehydrogenase protein isolated from rabbit muscle as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1:4,000-1:20,000, IP: 1:100, WB: 1:500-1:2,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: In lyophilized form PBS buffer with 0.01 % NaN3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Handhabung: Avoid repeated freeze/thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage

Referenzen

Uddin, Zou, Sharma, Gatla, Vancurova: "Proteasome inhibition induces IKK-dependent interleukin-8 expression in triple negative breast cancer cells: Opportunity for combination therapy." in: PLoS ONE, Vol. 13, Issue 8, pp. e0201858, (2019) (PubMed).

Sanacora, Urdinez, Chang, Vancurova: "Anticancer drug bortezomib increases interleukin-8 expression in human monocytes." in: Biochemical and biophysical research communications, Vol. 460, Issue 2, pp. 375-9, (2015) (PubMed).

Chang, Poltoratsky, Vancurova: "Bortezomib inhibits expression of TGF-β1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 6, pp. 2942-53, (2015) (PubMed).

Chang, Vancurova: "Bcl3 regulates pro-survival and pro-inflammatory gene expression in cutaneous T-cell lymphoma." in: Biochimica et biophysica acta, Vol. 1843, Issue 11, pp. 2620-30, (2014) (PubMed).

Manna, Singha, Phyo, Gatla, Chang, Sanacora, Ramaswami, Vancurova: "Proteasome inhibition by bortezomib increases IL-8 expression in androgen-independent prostate cancer cells: the role of IKKα." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 5, pp. 2837-46, (2013) (PubMed).

Juvekar, Manna, Ramaswami, Chang, Vu, Ghosh, Celiker, Vancurova: "Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL." in: Molecular cancer research : MCR, Vol. 9, Issue 2, pp. 183-94, (2011) (PubMed).

Antigendetails

Target: LDH