Tyrosine Hydroxylase Antikörper
Kurzübersicht für Tyrosine Hydroxylase Antikörper (ABIN2855393)
Target
Alle Tyrosine Hydroxylase (TH) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio)
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Produktmerkmale
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Rabbit polyclonal antibody to Tyrosine Hydroxylase (tyrosine hydroxylase)
Tyrosine Hydroxylase antibody [N1C1] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human Tyrosine Hydroxylase. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IHC-Wm: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: IMR32
Validation: Orthogonal
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.57 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Tyrosine Hydroxylase (TH)
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Andere Bezeichnung
- tyrosine hydroxylase
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Hintergrund
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The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Molekulargewicht
- 59 kDa
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Gen-ID
- 7054
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UniProt
- P07101
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Pathways
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Target
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