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EEF1A2 Antikörper

Dieses Anti-EEF1A2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EEF1A2 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN2855358

Kurzübersicht für EEF1A2 Antikörper (ABIN2855358)

Target

Alle EEF1A2 Antikörper anzeigen
EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))

Reaktivität

  • 33
  • 16
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 36
  • 3
  • 1
Kaninchen

Klonalität

  • 39
  • 1
Polyklonal

Konjugat

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EEF1A2 Antikörper ist unkonjugiert

Applikation

  • 40
  • 19
  • 15
  • 13
  • 13
  • 9
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse

KO Validated
  • Spezifität

    Based on a BLAST result, it may also cross with human EEF1A1.

    Kreuzreaktivität

    Human, Maus, Ratte, Zebrafisch (Danio rerio)

    Produktmerkmale

    Rabbit Polyclonal antibody to EEF1A2 (eukaryotic translation elongation factor 1 alpha 2)
    EEF1A2 antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human EEF1A2. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: Mouse brain , mouse muscle , rat brain , 293T

    Validation: KO/KD

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.21 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Losada, Muñoz-Alonso, García, Sánchez-Murcia, Martínez-Leal, Domínguez, Lillo, Gago, Galmarini: "Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin." in: Scientific reports, Vol. 6, pp. 35100, (2018) (PubMed).

  • Target

    EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))

    Andere Bezeichnung

    eukaryotic translation elongation factor 1 alpha 2

    Hintergrund

    This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Nucleus

    Molekulargewicht

    50 kDa

    Gen-ID

    1917

    UniProt

    Q05639
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