FOXM1 Antikörper
Kurzübersicht für FOXM1 Antikörper (ABIN2855309)
Target
Alle FOXM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Kreuzreaktivität
- Human
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Produktmerkmale
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Rabbit Polyclonal antibody to FOXM1 (forkhead box M1)
FOXM1 antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human FOXM1. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: FOXM1-transfected 293T
Validation: KO/KD, Orthogonal, Overexpression
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.12 mg/mL
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Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cells." in: Molecular biology of the cell, Vol. 31, Issue 6, pp. 419-438, (2020) (PubMed).
: "FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter." in: Molecular therapy oncolytics, Vol. 14, pp. 196-212, (2019) (PubMed).
: "Chromatin associated SETD3 negatively regulates VEGF expression." in: Scientific reports, Vol. 6, pp. 37115, (2018) (PubMed).
: "CDC20 maintains tumor initiating cells." in: Oncotarget, Vol. 6, Issue 15, pp. 13241-54, (2016) (PubMed).
: "Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells." in: Genome biology, Vol. 14, Issue 1, pp. R6, (2014) (PubMed).
: "
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Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cells." in: Molecular biology of the cell, Vol. 31, Issue 6, pp. 419-438, (2020) (PubMed).
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- FOXM1 (Forkhead Box M1 (FOXM1))
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Andere Bezeichnung
- forkhead box M1
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Hintergrund
- Cellular Localization: Nucleus
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Molekulargewicht
- 84 kDa
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Gen-ID
- 2305
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UniProt
- Q08050
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Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
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