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FOXM1 Antikörper

Der Kaninchen Polyklonal Anti-FOXM1-Antikörper wurde für WB, IP, ChIP und IHC (p) validiert. Er ist geeignet, FOXM1 in Proben von Human zu detektieren. Es sind 5+ Publikationen verfügbar.
Produktnummer ABIN2855309

Kurzübersicht für FOXM1 Antikörper (ABIN2855309)

Target

Alle FOXM1 Antikörper anzeigen
FOXM1 (Forkhead Box M1 (FOXM1))

Reaktivität

  • 50
  • 25
  • 22
  • 4
  • 3
  • 2
  • 2
  • 2
Human

Wirt

  • 40
  • 13
Kaninchen

Klonalität

  • 38
  • 15
Polyklonal

Konjugat

  • 33
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser FOXM1 Antikörper ist unkonjugiert

Applikation

  • 26
  • 20
  • 10
  • 7
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse

KO Validated
  • Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to FOXM1 (forkhead box M1)
    FOXM1 antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human FOXM1. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: FOXM1-transfected 293T

    Validation: KO/KD, Orthogonal, Overexpression

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.12 mg/mL

    Buffer

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Manzione, Rombouts, Steklov, Pasquali, Sablina, Gelens, Qian, Bollen: "Co-regulation of the antagonistic RepoMan:Aurora-B pair in proliferating cells." in: Molecular biology of the cell, Vol. 31, Issue 6, pp. 419-438, (2020) (PubMed).

    Huang, Zhang, Jiang, Zhang, Xiang, Ren: "FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter." in: Molecular therapy oncolytics, Vol. 14, pp. 196-212, (2019) (PubMed).

    Cohn, Feldman, Weil, Kublanovsky, Levy: "Chromatin associated SETD3 negatively regulates VEGF expression." in: Scientific reports, Vol. 6, pp. 37115, (2018) (PubMed).

    Xie, Wu, Mack, Yang, Kim, Hubert, Flavahan, Chu, Bao, Rich: "CDC20 maintains tumor initiating cells." in: Oncotarget, Vol. 6, Issue 15, pp. 13241-54, (2016) (PubMed).

    Sanders, Ross-Innes, Beraldi, Carroll, Balasubramanian: "Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells." in: Genome biology, Vol. 14, Issue 1, pp. R6, (2014) (PubMed).

  • Target

    FOXM1 (Forkhead Box M1 (FOXM1))

    Andere Bezeichnung

    forkhead box M1

    Hintergrund

    Cellular Localization: Nucleus

    Molekulargewicht

    84 kDa

    Gen-ID

    2305

    UniProt

    Q08050

    Pathways

    Positive Regulation of Response to DNA Damage Stimulus
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