TALDO1 Antikörper (N-Term)

Produktnummer ABIN2855282

Produktdetails anti-TALDO1 Antikörper

Target: TALDO1 (Transaldolase 1 (TALDO1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TALDO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to Transaldolase (transaldolase 1)
Transaldolase antibody

Aufreinigung: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Transaldolase. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , Mouse brain

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 6.48 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-TALDO1 Antikörper (ABIN2855282)

Ding, Gong, Huang, Chen, Sui, Lin, Liang, Yuan, Xiang, Chen, Yin, Alexander, Wang, Song, Li, Wood, Wang: "Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers." in: Nature communications, Vol. 9, Issue 1, pp. 4274, (2018) (PubMed).

Details zu TALDO1

Target: TALDO1 (Transaldolase 1 (TALDO1))

Andere Bezeichnung: transaldolase 1 (TALDO1 Produkte)

Synonyme: TAL antikoerper, TAL-H antikoerper, TALDOR antikoerper, TALH antikoerper, Tal antikoerper, wu:fc32g02 antikoerper, zgc:56232 antikoerper, zgc:66054 antikoerper, EPS8L2 antikoerper, transaldolase antikoerper, TALDO1 antikoerper, taldo1 antikoerper, An07g03850 antikoerper, AO090020000520 antikoerper, transaldolase 1 antikoerper, transaldolase antikoerper, transaldolase 1 L homeolog antikoerper, Transaldolase 1 antikoerper, TALDO1 antikoerper, Taldo1 antikoerper, taldo1 antikoerper, LOC475937 antikoerper, taldo1.L antikoerper, talB antikoerper, RB3193 antikoerper, ANI_1_472064 antikoerper, AOR_1_906084 antikoerper, TAL1_1 antikoerper, Mrub_1361 antikoerper, Arnit_2857 antikoerper, Mesil_2037 antikoerper, Slip_2309 antikoerper, Acear_0056 antikoerper, Thena_1180 antikoerper, Halhy_0294 antikoerper, Mahau_0255 antikoerper, Isova_1495 antikoerper, talA.1 antikoerper, FsymDg_1707 antikoerper, Mesop_1203 antikoerper, Thein_0556 antikoerper

Hintergrund: Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

Cellular Localization: Cytoplasm

Molekulargewicht: 38 kDa

Gen-ID: 6888

UniProt: P37837