COBRA1 Antikörper (Center)

Produktnummer ABIN2855267

Der Kaninchen Polyklonal Anti-COBRA1-Antikörper wurde für WB, IF, IHC (p) und ICC validiert. Er ist geeignet, COBRA1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für COBRA1 Antikörper (Center) (ABIN2855267)

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktdetails anti-COBRA1 Antikörper

Bindungsspezifität: Center

Produktmerkmale: Rabbit Polyclonal antibody to COBRA1 (cofactor of BRCA1)
COBRA1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human COBRA1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: H1299

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Andere Bezeichnung: COBRA1

Hintergrund: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2, MIM 606026), either NELFC or NELFD (TH1L, MIM 605297), and NELFE (RDBP, MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1, MIM 603555) and SPT5 (SUPT5H, MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM]

Cellular Localization: Nucleus

Molekulargewicht: 66 kDa

Gen-ID: 25920