HNRNPAB Antikörper

Produktnummer ABIN2855199

Dieses Anti-HNRNPAB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HNRNPAB in WB, IF, IHC (p), ChIP-seq, ICC, IHC (wm) und IP. Geeignet für Human.

Kurzübersicht für HNRNPAB Antikörper (ABIN2855199)

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPAB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ChIP DNA-Sequencing (ChIP-seq), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm)), Immunoprecipitation (IP)

Güteklasse: KO Validated

Produktdetails anti-HNRNPAB Antikörper

Kreuzreaktivität: Human, Zebrafisch (Danio rerio)

Produktmerkmale: Rabbit Polyclonal antibody to hnRNP A/B (heterogeneous nuclear ribonucleoprotein A/B)
hnRNP A/B antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human hnRNP AB. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , 293T

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.26 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu HNRNPAB

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Andere Bezeichnung: heterogeneous nuclear ribonucleoprotein A/B

Hintergrund: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Cellular Localization: Nucleus

Molekulargewicht: 36 kDa

Gen-ID: 3182

UniProt: Q99729