GP120 Antikörper

Produktnummer ABIN285511

Dieser Ziege Polyklonal Antikörper detektiert spezifisch GP120 in ELISA, WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human Immunodeficiency Virus (HIV). Es wurde in 4+ Publikationen zitiert.

Kurzübersicht für GP120 Antikörper (ABIN285511)

Target: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Reaktivität: Human Immunodeficiency Virus (HIV)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GP120 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GP120 Antikörper

Aufreinigung: purified

Reinheit: > 95 % pure

Immunogen: HIV1 gp120 antibody was raised in goat using purified native gp120 from strain IIIB as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Protein A purified IgG fraction in 10 mM PBS, pH 7.2 with 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Referenzen für anti-GP120 Antikörper (ABIN285511)

Ikeda, Symeonides, Albin, Li, Thali, Harris: "HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G." in: PLoS pathogens, Vol. 14, Issue 4, pp. e1007010, (2018) (PubMed).

Usami, Wu, Göttlinger: "SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef." in: Nature, Vol. 526, Issue 7572, pp. 218-23, (2016) (PubMed).

Kondo, Melikyan: "Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells." in: PLoS ONE, Vol. 7, Issue 9, pp. e44827, (2013) (PubMed).

Miyauchi, Curran, Long, Kondo, Iwamoto, Engelman, Matsuda: "The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein." in: Retrovirology, Vol. 7, pp. 95, (2010) (PubMed).

Details zu GP120

Target: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Andere Bezeichnung: HIV1 Gp120

Substanzklasse: Viral Protein

Hintergrund: Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry.