LGALS1/Galectin 1 Antikörper

Produktnummer ABIN2855093

Der Kaninchen Polyklonal Anti-LGALS1/Galectin 1-Antikörper wurde für WB, ICC, IP, IF, IHC (p), IHC (fro) und IHC (wm) validiert. Er ist geeignet, LGALS1/Galectin 1 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für LGALS1/Galectin 1 Antikörper (ABIN2855093)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))

Güteklasse: KO Validated

Produktdetails anti-LGALS1/Galectin 1 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to Galectin 1 (lectin, galactoside-binding, soluble, 1)
Galectin 1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Galectin 1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NCI-H929 , BCL-1 , PC-12 , Rat2 , HeLa

Validation: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.52 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-LGALS1/Galectin 1 Antikörper (ABIN2855093)

Borowski, Tirado-Gonzalez, Freitag, Garcia, Barrientos, Blois: "Altered Glycosylation Contributes to Placental Dysfunction Upon Early Disruption of the NK Cell-DC Dynamics." in: Frontiers in immunology, Vol. 11, pp. 1316, (2020) (PubMed).

Paz, Joo, Chou, Fei, Mayo, Abdel-Azim, Ghazarian, Groffen, Heisterkamp: "Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 67, (2019) (PubMed).

Details zu LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Andere Bezeichnung: galectin 1

Hintergrund: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molekulargewicht: 15 kDa

Gen-ID: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis