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SAFB Antikörper

This anti-SAFB antibody (ABIN2855048) is a Rabbit Polyclonal antibody detecting SAFB in WB, IF, IHC (p), ICC. Suitable for Human.
Produktnummer ABIN2855048

Kurzübersicht für SAFB Antikörper (ABIN2855048)

Target

Alle SAFB Antikörper anzeigen
SAFB (Scaffold Attachment Factor B (SAFB))

Reaktivität

  • 36
  • 23
  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 40
  • 11
Kaninchen

Klonalität

  • 38
  • 13
Polyklonal

Konjugat

  • 32
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SAFB Antikörper ist unkonjugiert

Applikation

  • 34
  • 16
  • 14
  • 14
  • 13
  • 13
  • 9
  • 8
  • 7
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Rabbit polyclonal antibody to Scaffold attachment factor B1 (scaffold attachment factor B)
    Scaffold attachment factor B1 antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human SAFB. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: 293T , A431 , HeLa , HepG2

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    SAFB (Scaffold Attachment Factor B (SAFB))

    Andere Bezeichnung

    scaffold attachment factor B

    Hintergrund

    This gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.

    Cellular Localization: Nucleus

    Molekulargewicht

    103 kDa

    Gen-ID

    6294

    UniProt

    Q15424

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway
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