Glucose-6-Phosphate Dehydrogenase Antikörper
Kurzübersicht für Glucose-6-Phosphate Dehydrogenase Antikörper (ABIN2854975)
Target
Alle Glucose-6-Phosphate Dehydrogenase (G6PD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
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Rabbit Polyclonal antibody to G6PD (glucose-6-phosphate dehydrogenase)
G6PD antibody [N3C3] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human G6PD. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: HeLaS3 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12 , Rat2
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.81 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Glucose-6-Phosphate Dehydrogenase (G6PD)
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Andere Bezeichnung
- glucose-6-phosphate dehydrogenase
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Hintergrund
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This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 59 kDa
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Gen-ID
- 2539
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UniProt
- P11413
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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