This antibody is directed against the alpha-chain of glycophorin. It reacts with normoblasts and erythrocytes in indirect agglutination tests. No reaction occurs with En(a-) erythrocytes and other normal peripheral blood cells.
Aufreinigung
Purified
Reinheit
> 95 % pure
Immunogen
Factor XIII antibody was raised in sheep using purified human factor XIII as the immunogen.
F13
Reaktivität: Human, Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 350
Applikationshinweise
ELISA: 10 µg/mL, WB: 10 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Purified IgG supplied in Hepes buffered saline, pH 7.4, with 50 % Glycerol
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C.
Target
Factor XIII (F13)
(Coagulation Factor XIII (F13))
Andere Bezeichnung
Factor XIII
Hintergrund
Factor XIII is a transglutaminase that circulates in the plasma as a heterotetramer of two catalytic A subunits and two carrier B subunits. When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into factor XIIIa, its activation into Factor XIIIa requires calcium as a cofactor.