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Crk Antikörper (Center)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Crk in WB, IF und ICC. Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN2854888

Kurzübersicht für Crk Antikörper (Center) (ABIN2854888)

Target

Alle Crk (CRK) Antikörper anzeigen
Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

Reaktivität

  • 87
  • 22
  • 18
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 75
  • 12
Kaninchen

Klonalität

  • 73
  • 14
Polyklonal

Konjugat

  • 44
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Crk Antikörper ist unkonjugiert

Applikation

  • 64
  • 35
  • 27
  • 27
  • 16
  • 12
  • 9
  • 7
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 28
    • 15
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Kreuzreaktivität

    Rind (Kuh)

    Kreuzreaktivität (Details)

    Bovine (100 %)

    Produktmerkmale

    Rabbit Polyclonal antibody to CRK (v-crk sarcoma virus CT10 oncogene homolog (avian))
    CRK antibody [N2C3]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human CRK. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

    Kommentare

    Positive Control: 293T , A431 , H1299 , HepG2 , Raji , NIH-3T3

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))

    Andere Bezeichnung

    CRK

    Hintergrund

    This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

    Molekulargewicht

    34 kDa

    Gen-ID

    1398

    Pathways

    Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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