MUC4 Antikörper

Produktnummer ABIN2854862

Der Kaninchen Polyklonal Anti-MUC4-Antikörper wurde für IHC (p) validiert. Er ist geeignet, MUC4 in Proben von Human zu detektieren.

Kurzübersicht für MUC4 Antikörper (ABIN2854862)

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MUC4 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to Mucin 4 (mucin 4, cell surface associated)
Mucin 4 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Mucin 4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu MUC4

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Andere Bezeichnung: mucin 4, cell surface associated

Hintergrund: The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.

Cellular Localization: Membrane, Single-pass membrane protein (Potential) , Secreted

Molekulargewicht: 232 kDa

Gen-ID: 4585

UniProt: Q99102

Pathways: Regulation of Leukocyte Mediated Immunity