NPPB Antikörper

Produktnummer ABIN2854787

Der Kaninchen Polyklonal anti-NPPB Antikörper wird verwendet zum Nachweis von NPPB in Proben von Human. Er wurde validiert für WB, IF und ICC.

Kurzübersicht für NPPB Antikörper (ABIN2854787)

Target: NPPB (Natriuretic Peptide Precursor B (NPPB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-NPPB Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to BNP (natriuretic peptide precursor B)
BNP antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human BNP. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NPPB

Target: NPPB (Natriuretic Peptide Precursor B (NPPB))

Andere Bezeichnung: natriuretic peptide B

Hintergrund: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

Cellular Localization: Secreted

Molekulargewicht: 15 kDa

Gen-ID: 4879

UniProt: P16860

Pathways: Hormone Activity