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MVP Antikörper (C-Term)

Dieses Anti-MVP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MVP in WB und IHC (p). Geeignet für Human.
Produktnummer ABIN2854785

Kurzübersicht für MVP Antikörper (C-Term) (ABIN2854785)

Target

Alle MVP Antikörper anzeigen
MVP (Major Vault Protein (MVP))

Reaktivität

  • 111
  • 31
  • 29
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 72
  • 41
  • 1
Kaninchen

Klonalität

  • 66
  • 48
Polyklonal

Konjugat

  • 63
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Dieser MVP Antikörper ist unkonjugiert

Applikation

  • 58
  • 46
  • 37
  • 32
  • 26
  • 15
  • 13
  • 10
  • 9
  • 9
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse

KO Validated
  • Bindungsspezifität

    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Kreuzreaktivität

    Human, Maus

    Produktmerkmale

    Rabbit Polyclonal antibody to MVP/LRP (major vault protein)
    MVP/LRP antibody [C2C3], C-term

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the C-terminus region of human MVP/LRP. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: NIH-3T3 , HeLa

    Validation: KO/KD

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    MVP (Major Vault Protein (MVP))

    Andere Bezeichnung

    major vault protein

    Hintergrund

    This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences, however, the open reading frames are the same in both transcripts.

    Cellular Localization: Cytoplasm , Nucleus , nuclear pore complex

    Molekulargewicht

    99 kDa

    Gen-ID

    9961

    UniProt

    Q14764
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