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HRH4 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-HRH4-Antikörper wurde für WB validiert. Er ist geeignet, HRH4 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2854739

Kurzübersicht für HRH4 Antikörper (N-Term) (ABIN2854739)

Target

Alle HRH4 Antikörper anzeigen
HRH4 (Histamine Receptor H4 (HRH4))

Reaktivität

  • 58
  • 9
  • 3
  • 2
  • 1
Human

Wirt

  • 65
  • 3
Kaninchen

Klonalität

  • 65
  • 3
Polyklonal

Konjugat

  • 37
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HRH4 Antikörper ist unkonjugiert

Applikation

  • 54
  • 28
  • 16
  • 13
  • 13
  • 12
  • 12
  • 10
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Güteklasse

KO Validated
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit polyclonal antibody to Histamine H4 Receptor (histamine receptor H4)
    Histamine H4 Receptor antibody [N1N2], N-term

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H4 Receptor. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: Jurkat , Raji , NCI-H929 , human shHRH4-transfected HeLa cells

    Validation: KO/KD

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

  • Target

    HRH4 (Histamine Receptor H4 (HRH4))

    Andere Bezeichnung

    histamine receptor H4

    Hintergrund

    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors.

    Cellular Localization: Cell membrane, Multi-pass membrane protein

    Molekulargewicht

    44 kDa

    Gen-ID

    59340

    UniProt

    Q9H3N8
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