PDZD2 Antikörper (N-Term)
Kurzübersicht für PDZD2 Antikörper (N-Term) (ABIN2854591)
Target
Alle PDZD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Kreuzreaktivität
- Human
-
Produktmerkmale
-
Rabbit polyclonal antibody to PDZK3 (PDZ domain containing 2)
PDZK3 antibody [N1], N-term -
Aufreinigung
- Purified by antigen-affinity chromatography.
-
Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PDZK3. The exact sequence is proprietary.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Kommentare
-
Positive Control: A549
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
Konservierungsmittel
- Thimerosal (Merthiolate)
-
Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- PDZD2 (PDZ Domain Containing 2 (PDZD2))
-
Andere Bezeichnung
- PDZ domain containing 2
-
Hintergrund
-
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
Cellular Localization: Nucleus (By similarity) , Cytoplasm , Endoplasmic reticulum , Processed PDZ domain-containing protein 2: Secreted -
Molekulargewicht
- 302 kDa
-
Gen-ID
- 23037
-
UniProt
- O15018
Target
-