PPOX Antikörper

Produktnummer ABIN2854549

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PPOX in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PPOX Antikörper (ABIN2854549)

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PPOX Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to PPOX (protoporphyrinogen oxidase)
PPOX antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PPOX. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A549 , HCT116

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.82 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PPOX

Target: PPOX (Protoporphyrinogen Oxidase (PPOX))

Andere Bezeichnung: protoporphyrinogen oxidase

Hintergrund: This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Cellular Localization: Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side

Molekulargewicht: 51 kDa

Gen-ID: 5498

UniProt: P50336

Pathways: Synaptic Membrane, Feeding Behaviour