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LGI1 Antikörper

This anti-LGI1 antibody (ABIN2854526) is a Rabbit Polyclonal antibody detecting LGI1 in WB, IF, ICC. Suitable for Human.
Produktnummer ABIN2854526

Quick Overview for LGI1 Antikörper (ABIN2854526)

Target

Alle LGI1 Antikörper anzeigen
LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reaktivität

  • 42
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Human

Wirt

  • 28
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Kaninchen

Klonalität

  • 28
  • 23
Polyklonal

Konjugat

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  • 1
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  • 1
  • 1
Dieser LGI1 Antikörper ist unkonjugiert

Applikation

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Kreuzreaktivität

    Human, Ratte

    Produktmerkmale

    Rabbit polyclonal antibody to LGI1 (leucine-rich, glioma inactivated 1)
    LGI1 antibody [N2C2], Internal

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human LGI1. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: A431 , U87-MG , SK-N-SH , SK-N-AS , rat brain

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

    Andere Bezeichnung

    leucine rich glioma inactivated 1

    Hintergrund

    This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

    Cellular Localization: Secreted

    Molekulargewicht

    64 kDa

    Gen-ID

    9211

    UniProt

    O95970
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