LGI1 Antikörper

Produktnummer ABIN2854526

Der Kaninchen Polyklonal Anti-LGI1-Antikörper wurde für WB, IF und ICC validiert. Er ist geeignet, LGI1 in Proben von Human zu detektieren.

Kurzübersicht für LGI1 Antikörper (ABIN2854526)

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-LGI1 Antikörper

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Rabbit polyclonal antibody to LGI1 (leucine-rich, glioma inactivated 1)
LGI1 antibody [N2C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LGI1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , U87-MG , SK-N-SH , SK-N-AS , rat brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu LGI1

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Andere Bezeichnung: leucine rich glioma inactivated 1

Hintergrund: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

Cellular Localization: Secreted

Molekulargewicht: 64 kDa

Gen-ID: 9211

UniProt: O95970