APEH Antikörper (Center)

Produktnummer ABIN2854516

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch APEH in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für APEH Antikörper (Center) (ABIN2854516)

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APEH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-APEH Antikörper

Bindungsspezifität: Center

Kreuzreaktivität: Maus, Schwein, Ratte (Rattus)

Kreuzreaktivität (Details): Mouse (88 %), Pig (89 %), Rat (89 %)

Produktmerkmale: Rabbit polyclonal antibody to APEH (N-acylaminoacyl-peptide hydrolase)
APEH antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human APEH. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.34 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu APEH

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Andere Bezeichnung: APEH

Hintergrund: This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Cellular Localization: Cytoplasm

Molekulargewicht: 81 kDa

Gen-ID: 327