METTL3 Antikörper

Produktnummer ABIN2854497

Dieses Anti-METTL3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von METTL3 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für METTL3 Antikörper (ABIN2854497)

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METTL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-METTL3 Antikörper

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Rabbit polyclonal antibody to METTL3 (methyltransferase like 3)
METTL3 antibody [N2C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human METTL3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-METTL3 Antikörper (ABIN2854497)

Liang, Guan, Lin, Li, Geng, Li: "METTL3 serves an oncogenic role in human ovarian cancer cells partially via the AKT signaling pathway." in: Oncology letters, Vol. 19, Issue 4, pp. 3197-3204, (2020) (PubMed).

Details zu METTL3

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Andere Bezeichnung: methyltransferase like 3

Hintergrund: This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Cellular Localization: Nucleus speckle

Molekulargewicht: 64 kDa

Gen-ID: 56339

UniProt: Q86U44