CD1d Antikörper

Produktnummer ABIN2854492

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD1d in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD1d Antikörper (ABIN2854492)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD1d Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD1d Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to CD1D (CD1D molecule)
CD1D antibody [N2C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CD1D. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.91 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Andere Bezeichnung: CD1d molecule

Hintergrund: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.

Cellular Localization: Cell membrane , Endosome membrane , Lysosome membrane

Molekulargewicht: 38 kDa

Gen-ID: 912

UniProt: P15813

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process