FMO1 Antikörper

Produktnummer ABIN2854460

Der Kaninchen Polyklonal Anti-FMO1-Antikörper wurde für WB validiert. Er ist geeignet, FMO1 in Proben von Human zu detektieren.

Kurzübersicht für FMO1 Antikörper (ABIN2854460)

Target: FMO1 (Flavin Containing Monooxygenase 1 (FMO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FMO1 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to FMO1 (flavin containing monooxygenase 1)
FMO1 antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FMO1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu FMO1

Target: FMO1 (Flavin Containing Monooxygenase 1 (FMO1))

Andere Bezeichnung: flavin containing monooxygenase 1

Hintergrund: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.

Cellular Localization: Microsome membrane , Endoplasmic reticulum membrane

Molekulargewicht: 60 kDa

Gen-ID: 2326

UniProt: Q01740