ALAS2 Antikörper (Center)
Kurzübersicht für ALAS2 Antikörper (Center) (ABIN2854459)
Target
Alle ALAS2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Kreuzreaktivität
- Ratte (Rattus), Xenopus laevis, Zebrafisch (Danio rerio), Rind (Kuh), Xenopus tropicalis
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Kreuzreaktivität (Details)
- Rat (95 %), Xenopus laevis (81 %), Zebrafish (80 %), Bovine (95 %), Xenopus tropicalis (81 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to ALAS-E (aminolevulinate, delta-, synthase 2)
ALAS-E antibody [N3C3] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human ALAS-E. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Kommentare
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Positive Control: Raji , K562 , HL60 , mouse liver
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice." in: Frontiers in pharmacology, Vol. 5, pp. 79, (2014) (PubMed).
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: "H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice." in: Frontiers in pharmacology, Vol. 5, pp. 79, (2014) (PubMed).
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- ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
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Andere Bezeichnung
- ALAS-E
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Hintergrund
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The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Cellular Localization: Mitochondrion matrix -
Molekulargewicht
- 65 kDa
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Gen-ID
- 212
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Pathways
- Transition Metal Ion Homeostasis
Target
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