Aconitase 1 Antikörper
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- Target Alle Aconitase 1 (ACO1) Antikörper anzeigen
- Aconitase 1 (ACO1)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aconitase 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit Polyclonal antibody to Aconitase 1 (aconitase 1, soluble)
Aconitase 1 antibody [N1C1] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Aconitase 1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ACO1 Primärantikörper
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anti-Aconitase 1 (ACO1) (AA 251-443) antibody
ACO1 Reaktivität: Human WB, ELISA, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 329-443) antibodyACO1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (N-Term) antibodyACO1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 26-243) antibodyACO1 Reaktivität: Human WB, ELISA, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 508-745) antibodyACO1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 1-889) antibodyACO1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 780-889) antibodyACO1 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 2C1 unconjugated
anti-Aconitase 1 (ACO1) antibodyACO1 Reaktivität: Human, Maus, Ratte, Hamster WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 527-719) antibodyACO1 Reaktivität: Maus WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Aconitase 1 (ACO1) (AA 1-889) antibodyACO1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: A431 , HeLa , HepG2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.78 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Aconitase 1 (ACO1)
- Andere Bezeichnung
- aconitase 1 (ACO1 Produkte)
- Hintergrund
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Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
Cellular Localization: Cytoplasm - Molekulargewicht
- 98 kDa
- Gen-ID
- 48
- UniProt
- P21399
- Pathways
- Transition Metal Ion Homeostasis
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