Arylsulfatase B Antikörper
Kurzübersicht für Arylsulfatase B Antikörper (ABIN2854408)
Target
Alle Arylsulfatase B (ARSB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
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Rabbit polyclonal antibody to ARSB (arylsulfatase B)
ARSB antibody [N3C3] -
Aufreinigung
- Affinity purified by Protein A.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human ARSB. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: ARSB transfected 293T cell , HeLa , HepG2 , mouse placenta , rat testis
Validation: Overexpression
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 6.11 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Arylsulfatase B (ARSB)
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Andere Bezeichnung
- arylsulfatase B
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Hintergrund
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Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Cellular Localization: Lysosome -
Molekulargewicht
- 60 kDa
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Gen-ID
- 411
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UniProt
- P15848
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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