CDH6 Antikörper

Produktnummer ABIN2854396

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CDH6 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CDH6 Antikörper (ABIN2854396)

Target: CDH6 (K-Cadherin (CDH6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDH6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDH6 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to K-cadherin (cadherin 6, type 2, K-cadherin (fetal kidney))
K-cadherin antibody [N2C1], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human K-cadherin. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HeLa , Jurkat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CDH6

Target: CDH6 (K-Cadherin (CDH6))

Andere Bezeichnung: cadherin 6

Hintergrund: This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Cellular Localization: Cell membrane

Molekulargewicht: 88 kDa

Gen-ID: 1004

UniProt: P55285

Pathways: Cell-Cell Junction Organization