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MVK Antikörper

Dieses Anti-MVK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MVK in WB. Geeignet für Human.
Produktnummer ABIN2854359

Kurzübersicht für MVK Antikörper (ABIN2854359)

Target

Alle MVK Antikörper anzeigen
MVK (Mevalonate Kinase (MVK))

Reaktivität

  • 45
  • 8
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 40
  • 5
Kaninchen

Klonalität

  • 41
  • 4
Polyklonal

Konjugat

  • 29
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MVK Antikörper ist unkonjugiert

Applikation

  • 33
  • 17
  • 12
  • 12
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to MVK (mevalonate kinase)
    MVK antibody [N1C2]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human MVK. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: 293T

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    MVK (Mevalonate Kinase (MVK))

    Andere Bezeichnung

    mevalonate kinase

    Hintergrund

    This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.

    Cellular Localization: Cytoplasm , Peroxisome

    Molekulargewicht

    42 kDa

    Gen-ID

    4598

    UniProt

    Q03426
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