ODC1 Antikörper

Produktnummer ABIN2854335

Dieses Anti-ODC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ODC1 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für ODC1 Antikörper (ABIN2854335)

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ODC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ODC1 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit polyclonal antibody to ODC (ornithine decarboxylase 1)
ODC antibody [N3C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ODC. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.19 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-ODC1 Antikörper (ABIN2854335)

Sekiguchi, Seki, Kawai, Yoshida, Yoshida, Isobe, Hoshino, Shirai, Tanaka, Souzaki, Watanabe, Arakawa, Nannya, Suzuki, Fujii, Kataoka, Shiraishi, Chiba, Tanaka, Shimamura, Sato, Sato-Otsubo, Kimura et al.: "Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. ..." in: NPJ precision oncology, Vol. 4, pp. 20, (2020) (PubMed).

Details zu ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Andere Bezeichnung: ornithine decarboxylase 1

Hintergrund: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.

Molekulargewicht: 51 kDa

Gen-ID: 4953

UniProt: P11926