KISS1R Antikörper (C-Term)

Produktnummer ABIN2854280

Der Kaninchen Polyklonal Anti-KISS1R-Antikörper wurde für WB, ICC, IF und IHC (p) validiert. Er ist geeignet, KISS1R in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für KISS1R Antikörper (C-Term) (ABIN2854280)

Target: KISS1R (KISS1 Receptor (KISS1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KISS1R Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Rabbit polyclonal antibody to GPR54 (KISS1 receptor)
GPR54 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPR54. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-KISS1R Antikörper (ABIN2854280)

Francis, Abera, Matjila, Millar, Katz: "Kisspeptin regulation of genes involved in cell invasion and angiogenesis in first trimester human trophoblast cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e99680, (2015) (PubMed).

Details zu KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Andere Bezeichnung: KISS1 receptor

Hintergrund: The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Molekulargewicht: 43 kDa

Gen-ID: 84634

UniProt: Q969F8