CD52 Antikörper (PE)

Produktnummer ABIN2853610

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD52 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD52 Antikörper (PE) (ABIN2853610)

Target: CD52

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD52 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: BTG-2G

Produktdetails anti-CD52 Antikörper (PE)

Spezifität: This antibody reacts with mouse CD52 antigen.

Aufreinigung: Protein G agarose

Immunogen: IL-2Ralpha-transgenic mouse splenocyte

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 tests in 1 mL volume of PBS containing 1 % BSA and 0.09 % NaN3

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8 °C.

Details zu CD52

Target: CD52

Andere Bezeichnung: CD52 / CAMPATH-1

Hintergrund: CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

Gen-ID: 23833

NCBI Accession: NP_038734

UniProt: Q64389