Sema4a
Reaktivität: Human
WB, ELISA
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
PBS, 0.09 % NaN3, 1 % BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store in the dark at 2-8 °C.
Target
Sema4a
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))
Andere Bezeichnung
SEMA4A
Hintergrund
Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses. Sema4A, a class IV semaphorin that was originally identified as SemB, is a transmembrane protein expressed by dendritic cells and B cells. Sema4A enhances the activation and differentiation of T cells and generation of antigen-specific T cells via interaction with its receptor, Tim-2.Synonyms: SEMAB, SEMB, Sema B, Semaphorin-4A, Semaphorin-B